注冊

Notch信號通路ChIP PCR芯片 Notch Signaling Pathway ChIP PCR Array

科技服務(wù) > 生物芯片實驗服務(wù) > Notch信號通路ChIP PCR芯片 Notch Signaling Pathway ChIP PCR Array

Notch信號通路ChIP PCR芯片 Notch Signaling Pathway ChIP PCR Array

聯(lián)系購買

配送服務(wù)：

運費￥0.00

數(shù)量：

（庫存 9999 件）

產(chǎn)品詳細(xì)

地區(qū)：	上海
簡介：	Notch Signaling Pathway ChIP PCR Array
提供商：	SAB
服務(wù)名稱：	Notch Signaling Pathway ChIP PCR Array

Notch Signaling Pathway ChIP PCR Array
The The Human Notch Signaling Pathway EpiTect ChIP qPCR Array profiles the histone modification status or “histone code” of 84 genes key to Notch signal transduction. Histone modifications regulate chromatin structure and correlate with the transcriptional activity of associated genes. The Notch pathway includes 4 Notch receptors that are activated by ligands from the Jagged and Delta families. These receptors are cleaved and translocate to the nucleus, where they interact with co-activator and co-repressor complexes to control target genes. Histone modifications epigenetically regulate some Notch target genes, affecting their ability to be induced or repressed by Notch. Core Notch signaling genes may be regulated in a similar manner. Notch signaling mediates cell–cell communication and developmental processes, and interacts with other developmental signaling pathways such as Hedgehog and Wnt. This array includes genes involved in Notch signaling as well as Notch targets. Genes from other signaling pathways that cross-talk with the Notch signaling pathway are also represented. Using chromatin immunoprecipitation and this real-time PCR array, research studies can easily and reliably analyze the histone modification patterns associated with a focused gene panel involved in Notch signaling

Notch Signaling Pathway:
Notch Ligands and Cofactors: ADAM17 (CD156B), JAG2, LFNG, MFNG, NOTCH1, NOTCH2, NOTCH3, NOTCH4, RFNG.
Notch Receptor Processing: ADAM10, APH1A, DTX1, DVL1, NCSTN, NUMB, PSEN1, PSEN2, PSENEN (PEN2).
Notch Transcription Factors and Cofactors: KAT2B, MAML1, MAML2, NCOR2, RBPJL, SNW1 (SKIIP).
Notch Signaling Pathway Target Genes:
Apoptosis Genes: CDKN1A, CFLAR (CASH), IL2RA, NFKB1, PTCRA.
Cell Cycle Regulators: CCND1, CDKN1A, IL2RA.
Cell Proliferation: CDKN1A, ERBB2, FOSL1, IL2RA.
Genes Regulating Cell Differentiation: DTX1, PPARG.
Neurogenesis: HES1, HES5, HEY1, HEY2.
Regulation of Transcription: DTX1, FOS, FOSL1, HES1, HES5, HEY1, HEY2, ID1, NFKB1, NFKB2, NR4A2, PPARG, STAT6.
Immune Response: CHUK, IFNG, IL17B, NFKB1.
Other Target Genes with Unspecified Functions: CD44, KRT1, LOR.
Notch Signaling Processes:
Apoptosis: AXIN1, EP300, HDAC1, NOTCH2, PSEN1, PSEN2.
Cell Cycle Regulators: AXIN1, CCNE1, EP300, FIGF (VEGFD), JAG2, KAT2B, NOTCH2.
Cell Proliferation: FIGF, FZD3, JAG2, KAT2B, LRP5, MMP7, NOTCH2, STIL (SIL).
Regulation of Cell Differentiation: JAG2, LMO2, NOTCH1, NOTCH2, NOTCH3, NOTCH4, PAX5, SHH.
Neurogenesis: EP300, HEYL, NEURL, NOTCH2, PAX5, RFNG.
Regulation of Transcription: AES (GRG5), CBL, CTNNB1, EP300, GLI1, HDAC1, HEYL, HR, KAT2B, NCOR2, NOTCH1, NOTCH2, NOTCH3, NOTCH4, PAX5, POFUT1, RUNX1, SUFU, TEAD1, TLE1.
Immune Response: GBP2, IL2RA, SH2D1A.
Other Gene: SEL1L.
Other Signaling Pathways that Crosstalk with the Notch Signaling Pathway:
Sonic Hedgehog (Shh) Pathway: GLI1, GSK3B, SHH, SMO, SUFU.
Wnt Receptor Signaling Pathway: AES (GRG5), AXIN1, CTNNB1, FZD1, FZD2, FZD3, FZD4, FZD6, FZD7, GSK3B, LRP5, TLE1, WISP1, WNT11.

在線留言

姓名

電話號碼

電子郵箱

公司名稱

地址

留言*

提交

上一個： Notch信號通路DNA甲基化PCR芯片 Notch Signaling Pathway DNA Methylation PCR Array

下一個：原癌基因和抑癌基因PCR芯片Oncogenes & Tumor Suppressor Genes ChIP PCR Array

TOP

谷小姐

戴小姐

4006966643

daihp@yingbio.com

日本做爰无遮A片免费,扌喿辶畐的日本,鲁大师在线观看日本电影,《内衣办公室》日本动漫,巜饥渴的人妻日本》中字,强壮的公次次弄得我高潮A片日本

Notch信號通路ChIP PCR芯片 Notch Signaling Pathway ChIP PCR Array

Notch信號通路ChIP PCR芯片 Notch Signaling Pathway ChIP PCR Array